GammaCore Therapy

Stimulate the vagus nerve to stop migraines and improve health overall

One Device, Many Uses

GammaCore Sapphire™ is the first and only FDA cleared non-invasive device to treat and prevent multiple types of headache pain via the vagus nerve. It’s small, handheld and portable for quick and easy treatments whenever and wherever needed.

Backed by Research

Vagus nerve stimulation has been widely researched and studied. The GammaCore device itself has 7 different FDA clearances with robust scientific & clinical data to support its safe and effective use, including more than 7 randomized controlled clinical trials, over 30 mechanisms of action peer-reviewed papers, and 40-plus peer-reviewed clinical papers.

How It Works

Unlike traditional vagus nerve stimulation, gammaCore non-invasive vagus nerve stimulator (nVNS) activates the vagus nerve with gentle electrical stimulation through the skin to prevent and relieve headache pain, without the need for surgery.

Why simulate the vagus nerve? Think of the vagus nerve as the “superhighway” of the nervous system. This important highway sends communications between your brain and many parts of the body.

Stimulating the vagus nerve blocks the pain signals causing the attacks, to help provide fast relief and prevent future attacks.

What is the Vagus Nerve?

The vagus nerve is the longest cranial nerve in the body, with branching nerves that carry messages between the brain and the heart, lungs, stomach, and many other organs. It is a sensory and motor nerve, responsible for reporting information to the brain and transmitting instructions back to the body’s organs.

Think of the vagus nerve as the nervous systems “super-highway”, sending important communication between your brain and many parts of the body and back. It facilitates and communicates with many different systems, operating and influencing things like pain regulation, anxiety, fatigue, heart rate, digestive track activity, and lung function. The greatest significance of the vagus nerve is that it is a key part of the parasympathetic nervous system, which controls the body’s rest and digest, repair functions.

New studies also suggest that some long COVID-19 symptoms, including persistent voice problems, difficulty swallowing, dizziness, low blood pressure, and high heart rates may be linked to the effect of the virus on the vagus nerve.

GammaCore Therapy